FFH Metabolomics News | May 2017

Postdoctoral Awards RFP. The Foods for Health Discovery Theme is pleased to announce a call for proposals for 50% support for up to three (3) postdoctoral fellows for one year beginning August 2017. Recipients will each work on a collaborative project that uses metabolomics/foodomics and preferably one or more other omic technologies (genomics/ epigenomics/ metagenomics; transcriptomics/ metatranscriptomics; proteomics). The project should address a relevant problem in the food-nutrition-health axis and represent collaboration between two or more faculty affiliates in the FFH initiative. The support is expected to result in the development of a competitive proposal submitted to a federal agency or industrial sponsor, one or more first authored manuscripts and presentation of results at the annual meeting of the Metabolomics Society and/or an international conference on metabolomics. View RFP

Seed Grant Awards.  Congratulations to the recipients of the Spring 2017 FFH-FIC seed grant awards! A total of $125,000 was awarded for proposals of $25,000 each to advance transdisciplinary collaboration and scientific approaches integrating foods and nutrition, metabolomics, and health.

  • Brian Ahmer, Associate Professor, Department of Microbial Infection and Immunity. Impacts of Salmonella infection on the chemical and biological landscape of the gut. Co-PIs: Vicki Wysocki, Kelly Wrighton.
  • David Francis, Professor, Department of Horticulture and Crop Sciences. Metabolomic and Transcriptional Responses to Diets Containing Red or Tangerine Tomatoes. Co-PIs: Steven Clinton, Jessica Cooperstone.
  • Tonya Orchard, Assistant Professor, Department of Human Sciences. The Effects of Dietary Modification on the Brain Lipidome after Chemotherapy. Co-PIs: Rachel Kopec, Courtney DeVries.
  • Sandra Velleman, Professor, OARDC Animal Sciences. Using targeted and broad-spectrum metabolomics to identify metabolism-based changes leading to decreased meat quality in fast growing turkeys. Co-PIs: Daniel Clark, Joshua Blakeslee.
  • Christopher Weghorst, Professor, College of Public Health. Functional Foods and Oral Cancer Prevention: Hybrid NMR-MS Metabolic Signature of Experimental Oral Carcinogenesis and Black Raspberry Chemoprevention. Co-PIs: Thomas Knobloch, Steve Oghumu, Rafael Brüschweiler, Arpad Somogyi.

Inaugural Conference on Food and Nutritional Metabolomics for Health. The Joint Meeting of the Inaugural Conference on Food and Nutritional Metabolomics and 14th Annual Ohio Mass Spectrometry Symposium was held on May 17-18, 2017 at the Ohio Union. 234 individuals representing 42 organizations participated in the two-day event. Academic and industrial researchers presented findings, shared information, and sparked new collaborations in the rapidly advancing fields of metabolomics and mass spectrometry. The conference agenda included keynote speakers, Dr. Gary Patti (Washington University in St. Louis) and Dr. Robert Gerszten (Harvard University); plenary speakers, Ohio State’s Dr. Rafael Brüschweiler, Dr. Ewy Mathé, and Dr. Devin Peterson; "Lunch and Learn" sessions; oral and poster sessions; opportunities for academia-industry interaction; and an evening reception. An Introduction to Metabolomics tutorial preceded the conference. The Metabolomics Society and the scientific journal, Metabolites, were media partners for the event. Sponsors included Advion, Agilent Technologies, Bruker Daltonics, McCormick Science Institute, Mead Johnson Nutrition, Nestle, PanTheryx, Inc, SCIEX, JM Smucker, Thermo Fisher Scientific, and Waters Corporation.  View conference program 

Awards. The following Ohio State metabolomics researchers have received recent awards: 

  • Emmanuel Hatzakis, Assistant Professor, Dept. of Food Science and Technology, has been named the 2017 recipient of the Samuel Cate Prescott Award from Institute of Food Technologists (IFT), for demonstrating outstanding ability in research in an area of food science and technology. He will be recognized during the IFT Annual Meeting in June.
  • Haley Chatelaine, graduate student in the Division of Human Nutrition, received a Dannon Fellowship which provides $25,000 in stipend support. The project, Investigations of the microbiome metabolome as influenced by the consumption of probiotic yogurt, will be done in collaboration with microbiome expert ZT Yu, Professor in the Dept. of Animal Sciences. Haley is co-advised by Rachel Kopec and Emmanuel Hatzakis. 
  • Rachel Kopec, Assistant Professor, Human Nutrition, was selected to attend the Dannon Institute Nutrition Leadership Institute in early June. This program focuses on developing leadership skills and is targeted toward nutrition scientists.
  • Vicki Wysocki, Professor, Dept. of Chemistry and Biochemistry, Director of CCIC, and Ohio Eminent Scholar, received the 2017 Frank H. Field and Joe L. Franklin Award for Outstanding Achievement at the national meeting of the American Chemical Society in San Francisco in April. The award, sponsored by Waters Corp, recognizes Dr. Wysocki's outstanding accomplishments in the development of surface-induced dissociation for native mass spectrometry structural characterization of noncovalent complexes.

Publications. The following metabolomics research involves Ohio State researchers: 

Funding Opportunities

FFH-FIC Team Awards. An RFP is open for proposals to support new or existing multi-college teams of researchers in the development of ideas to further a common research interest (e.g. team meetings, hosting visiting colleagues, sponsoring a workshop, hiring a facilitator). It is anticipated that these activities will lead to new collaborative proposals for grants advancing FFH and FIC missions, such as those listed below. Download RFP

NIH Funding Opportunities

Spotlight on Metabolomics in Systems Biology

Modeling complex biological systems requires a collaborative, integrative approach. For an outstanding overview of how metabolomics gives researchers the tools to better understand molecular phenotypes and explore the effects of interactions between genes and environmental factors, check out the following article from the May 12, 2017 issue of Science, Big data, big picture: Metabolomics meets systems biology


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