CBI Research Day

Join researchers, clinicians, and trainees to share, discuss, and connect at the annual CBI Research Day. This flagship scientific event for brain injury research features invited and local speakers, poster presentations, and updates on program and pilot projects. We invite all Ohio State faculty, staff, and students to attend. CME credits are available.

CBI Research Day | March 10, 2021

REGISTRANTS CAN ACCESS THE CONFERENCE VIA PASSWORD-PROTECTED LINKS IN THE SCHEDULE SECTION BELOW.

Congratulations to our 2021 Poster Winners!

Best Undergraduate Poster

Antonia Zouridakis of the Tedeschi Lab - Harnessing structural and functional reorganization of neuronal circuits after stroke

Best Graduate Poster

Brigette Gonzalez Olmo of the Barrientos Lab - Short-term high-fat diet consumption impairs long-term potentiation in the aged hippocampus

Best Staff Poster

Angela R. Filous of the Schwab Lab - Acquired pneumonia leads to functional deficits after SCI

KEYNOTE: Amy K. Wagner, MD

ENDOWED CHAIR FOR TRANSLATIONAL RESEARCH
PHYSICAL MEDICINE & REHABILITATION
UNIVERSITY OF PITTSBURGH

Rehabilomics Research: Towards a Precision Medicine Approach to Optimizing Function after Acquired Brain Injury

Dr. Wagner's research program uses biomarkers as tools for developing and optimizing personalized treatments and outcomes for individuals with disability, particularly with traumatic brain injury (TBI) and with cardiac arrest. Dr. Wagner's research focus includes the TBI Rehabilomics Research Model, identifying biomarkers relevant for assessing pathology and prognosis as well as for assessing clinical risk and use in clinical decision making.

SPOTLIGHT: CHRISTINE MAC DONALD, PHD

ENDOWED CHAIR & PROFESSOR OF NEUROLOGIC SURGERY
RESEARCH DIRECTOR, THE SPORTS INSTITUTE
UNIVERSITY OF WASHINGTON

Combat-related Concussion: Understanding trajectories of long-term clinical and neuroimaging outcome

Dr. Mac Donald's research is focused on advanced MRI methods and the application of these imaging methods to traumatic brain injury (TBI) and neurodegenerative disease. Her current research includes advanced neuroimaging evaluation of mild traumatic brain injury in the US military, severe brain injury in adult civilians, and the distribution of brain injury in children with particular emphasis on comorbid mental health conditions following concussion.

SPOTLIGHT: CARRIE LYNN ESOPENKO, PHD

ASSISTANT PROFESSOR OF REHABILITATION & MOVEMENT SCIENCES
RUTGERS UNIVERSITY

Examining the Brain and Behavioral Effects of IPV-related Head Trauma

Dr. Esopenko is the Principal Investigator the for Rutgers University New Brunswick's involvement in the Big Ten/Ivy League TBI Epidemiology Study Consortium. Additionally, she one of two Big 10 PIs on the Study Advisory Committee for the Big 10/Ivy League Epidemiology Study and a Board Member on the Ivy League/Big 10 TBI Collaboration. Dr. Esopenko is also the lead investigator for the am a member of Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium IPV working group, co-lead investigator for the ENIGMA COVID-19 working group, and member of the Brain Injury and Sports-Related Concussion working groups.

SPOTLIGHT: JIYEON DENNINGER, MD, PHD

Defining the adult hippocampal neural stem cell secretome

SPOTLIGHT: MICHAEL BUTLER, PHD

DHA prevents diet-induced memory impairments in aged rats and microglial inflammatory gene expression

SPOTLIGHT: RACHEL GILFARB

Effects of reproductive experience on acute neuroimmune outcomes following traumatic brain injury in mice

CONFERENCE DETAILS

CBI RESEARCH DAY 2021 SCHEDULE
MARCH 10, 2021, 8:00AM-4:15PM

08:00AM-08:30AM WELCOME & OPENING REMARKS
ZOOM LINK

08:30AM-10:15AM SPOTLIGHT TALKS
ZOOM LINK

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10:30AM-11:00AM DATA BLITZ
ZOOM LINK

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11:15AM-12:15PM KEYNOTE ADDRESS
ZOOM LINK

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01:00PM-02:00PM RESEARCH PITCHES
ZOOM LINK

02:00PM-04:00PM POSTER SESSION & SOCIALS
GATHER LINK

04:00PM-04:15PM CLOSING REMARKS
GATHER LINK

TRAINEE SPOTLIGHTS

Defining the adult hippocampal neural stem cell secretome
Jiyeon Denninger, MD, PhD | Postdoctoral Researcher | Department of Psychology
MENTOR: Liz Kirby
I study therapeutically relevant aspects of adult neural stem cell biology at basline and upon injury.

DHA prevents diet-induced memory impairments in aged rats and microglial inflammatory gene expression
Michael Butler, PhD | Postdoctoral Researcher | Institute of Behavioral Medicine Research
MENTOR: Ruth Barrientos
I study the impacts of aging and nutrition on neuroinflammation and learning and memory.

Effects of reproductive experience on acute neuroimmune outcomes following traumatic brain injury in mice
Rachel Gilfarb | Graduate Student | Department of Psychology
MENTOR: Benedtta Leurner
I study how TBI different affects the brain following pregnancy and motherhood experience.

DATA BLITZ

Impaired Glial IL-10 / TGFβ Signaling Underlies the Exaggerated Sickness Response in Aged Mice
Shane O'Neil | Graduate Student | Department of Neuroscience
MENTOR: Jonathan Godbout
My work focuses on the effects of age-associated dysfunction on neuroinflammation.

TLR4 Antagonism Ameliorates Persistent Post-Operative Cognitive Decline
Stephanie Muscat | Graduate Student | Institute of Behavioral Medicine Research
MENTOR: Ruth Barrientos
I study the mechanisms by which peripheral immune challenges (e.g. surgery, infection) can induce cognitive impairment

Chronic cortical inflammation and cognitive impairment associated with diffuse brain injury is ameliorated by forced turnover of microglia
Chelsea Bray | Research Staff | Department of Neuroscience
MENTOR: Jonathan Godbout
My expertise lies in murine models of traumatic brain injury, with which I study neuroimmunology and it's effects on functional recovery post-injury.

Aptamer Functionalization for neurotransimitter detection
Sam Gillespie | Undergraduate Student | Department of Materials Science and Engineering
MENTOR: Jinghua Li
I study gold electrode functionalization

Innate organization of the human brain
Fiona Molloy | Graduate Student | Department of Psychology
MENTOR: Zeynep Saygin
I study cognitive neuroscience in infants and adults using neuroimaging and computational modeling.

Resolving Misalignment Limitations of Wireless and Batteryless Brain Implants
Mihir Patil | Graduate Student | Department of Electrical and Computer Engineering
MENTOR: Asimina Kiourti
I design wireless and batteryless implants for neurosensing.

Using video footage to characterize potential concussive events in soccer
Tara Porfido | Graduate Student | Department of Rehabilitation and Movement Sciences
MENTOR: Carrie Esopenko
I am a physical therapist and my work focuses on methods to prevent, identify, and characterize sports-related potential concussive events.

Leveraging photoelicitation methods to elucidate resilience among adults with co-occurring traumatic brain injury and opioid use disorder
Kathryn Coxe | Graduate Student | College of Social Work
MENTOR: Audrey Begun
Implementation of TBI-best care practices in behavioral health

Our conference will feature several pitches by researchers at Ohio State and partner organizations aimed to raise the visibility of - and engagement in - novel translational initiatives that address brain injury survivorship. Join us at 1:00PM to learn more about these exciting opportunities!

Strategic Initiatives at Ohio State's Neuroscience Research Institute
Erica Bell, PhD

Brain, Body, and Behavioral Health in First Responders: The HERO Survey
Nathan Edwards, MS

The active role of sleep brain dynamics after stroke: a working hypothesis
Paola Malerba, PhD

Building an OSU translational research program to address chronic brain injury resulting from interpersonal violence
Julianna Nemeth, PhD

POSTER POSITION POSTER HOUR FIRST LAST ABSTRACT TITLE
1 2PM Chelsea Bray Chronic cortical inflammation and cognitive impairment associated with diffuse brain injury is ameliorated by forced turnover of microglia
2 3PM Michael Butler DHA prevents diet-induced memory impairments in aged rats and microglial inflammatory gene expression
3 2PM Kathryn Coxe Leveraging photoelicitation methods to elucidate resilience among adults with co-occurring traumatic brain injury and opioid use disorder
4 3PM Nicholas Deems Post-surgical morphine prolongs hippocampal dysfunction in aged rats: Implications for neuroinflammation and neuronal structure
5 2PM Jiyeon Denninger Defining the adult hippocampal neural stem cell secretome
6 3PM Angela Filous Acquired pneumonia leads to functional deficits after SCI
7 2PM Rachel Gilfarb Effects of reproductive experience on acute neuroimmune outcomes following traumatic brain injury in mice
8 3PM Sam Gillespie Aptamer Functionalization for neurotransimitter detection
9 2PM Brigitte Gonzalez Olmo Short-term high-fat diet consumption impairs long-term potentiation in the aged hippocampus
10 3PM Alexander Hasselbach Partial Least Squares analysis of Alzheimer's disease biomarkers, modifiable health variables, and gray matter volume in older adults with Mild Cognitive Impairment
11 2PM Kelly Hiersche Examining the Relationship between Modifiable Health Variables and Cognition in Healthy Older Adults
12 3PM Jin Li Functional reorganization of the visual word form area in an individual born without the left superior temporal lobe
13 2PM Nashali Massa The effects of aging and high fat diet on intestinal inflammation and mitochondrial homeostasis
14 2PM Julia Mazzarella Speed and Straightness of Reach Change with Different Functional Tasks in Typically Developing Children
15 2PM Fiona Molloy Innate organization of the human brain
16 3PM Stephanie Muscat TLR4 Antagonism Ameliorates Persistent Post-Operative Cognitive Decline
17 2PM Julianna Nemeth Brain Injury, Regulating Cognition and Affect in Response to Stressors, Food Insecurity, and Pro-smoking Social Situations: factors to consider in cessation intervention targeted to the needs of homeless youth
18 3PM Shane O'Neil Impaired Glial IL-10 / TGFβ Signaling Underlies the Exaggerated Sickness Response in Aged Mice
19 2PM Jonathan Packer Chronic inflammation and Cognitive Deterioration after Diffuse Brain Injury are dependent on activation of the Stimulator of Interferon Genes (STING) and increased type I interferon signaling.
20 3PM Mihir Patil Resolving Misalignment Limitations of Wireless and Batteryless Brain Implants
21 2PM Kristen Pechacek Minocycline is ineffective in treating brain injury-induced impulsive and attention deficits
22 3PM Tara Porfido Using video footage to characterize potential concussive events in soccer
23 2PM Allyanna Rice Bio-Matched Antennas for Non-Invasive Brain Temperature Sensing
24 3PM Zoe Tapp Sleep Fragmentation Enhances Inflammation and Compromises Stress-Responsive Neuronal Activity Following Traumatic Brain Injury
25 2PM Sarah Wampler Brain Injury in Female Rats Increases Impulsivity on the Rodent Gambling Task but is not Treated by Neuromodulation
26 3PM Antonia Zouridakis Harnessing structural and functional reorganization of neuronal circuits after stroke

This year's conference will be entirely virtual, and will use two web conferencing tools. All conference activities except the poster session will use Zoom webinars and meetings.

Aside from our invited speakers, we will select a number of presenters from the abstract pool to give short Spotlights (n=3, 8 minutes each) and Data Blitz talks (n=8, 3 minutes each).

Research pitches will feature invited CBI affiliates and colleagues from partner institutions to present ideas for new lines of interdisciplinary research and collaborative projects.

The poster session will use Gather, an interactive platform that combines video conferencing, file sharing for PDF posters and discussion socials, and 8-bit gaming. We hope to make this a fun and immersive experience. Through this set up, posters will be live judged, and discussion sessions can be held ad-hoc in a variety of locations.

REGISTER TO ATTEND by March 1, 2021

SUBMIT ABSTRACTS FOR TALKS by February 15, 2021

SUBMIT ABSTRACTS FOR POSTERS by February 24, 2021

DISCLOSURE STATEMENT

At the conclusion of this event, learners will be able to:

  • Describe the prevalence and incidence of chronic brain injury in the general population and in at-risk groups
  • List 3 approaches for treating brain injury as a chronic condition
  • List 3 types of persistent symptoms following concussion
  • Describe mechanisms of neural regeneration following injury
  • List 3 academic and community partners in the area providing services to brain injury survivors

ACCREDITATION STATEMENT

The Ohio State University Center for Continuing Medical Education (CCME) is accredited by the Accreditation Council for Continuing Medical Education (ACCME®) to provide continuing medical education for physicians.

AMA DESIGNATION STATEMENT

The Ohio State University Center for Continuing Medical Education (CCME) designates this live activity for a maximum of 4.25 AMA PRA Category 1 Credit(s) ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.