Chronic Brain Injury


Our brain is the body’s most complex organ. It makes us who we are. It is critical to our abilities to speak, think, remember, interact and move. Even mild brain injuries can have persistent, chronic effects that affect future health and wellbeing. However, the detection of the extent, phase and severity of brain injury continues to be elusive.

To accelerate discovery, more than 250 experts in the fields of engineering, psychology, neuroscience, speech and hearing science, rehabilitation and medicine are forming and scaling teams to translate knowledge, and expand capacity to implement practical solutions through public-private partnerships.  We are:

  • Developing methods for detecting the presence and extent of brain injuries and chronic neurodegenerative diseases with real-time monitoring of “rare” biological moieties
  • Deepening an understanding of why even mild brain injuries (e.g., concussions) have persistent, chronic effects that can provoke early-onset dementia, and developing personalized interventions in the case of injury.
  • Understanding the effects on cognitive abilities, psychological wellbeing and social competence from trauma on the brain’s structures and functions, and conditions like Alzheimer Disease.
  • Creating new and improved approaches and techniques for imaging the brain with emerging sensor technologies and data analysis methods, and breakthroughs in neural interfacing technology, neural prosthetics and biotronic engineering technologies.
  • Studying the role of immune cells and responses after traumatic brain injury to develop intervention strategies to decrease brain damage and translate NIH-funded clinical trials for acute neurological conditions into best practice assessment techniques.

Ohio State is advancing how we understand and approach brain injury — from molecular investigations in the laboratory to clinical applications at patients’ bedsides.

Program Leads

Faculty Lead

Randy Nelson, PhD

Program Manager

Kedar Hiremath


Chronic Brain Injury

Ohio State Wexner Medical Center Awarded Spinal Cord Injury Grant

The Ohio State University Wexner Medical Center has been awarded a five-year, $2.2-million grant from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) to build the Ohio Regional Spinal Cord Injury Model System.

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Chronic Brain Injury

CBI affiliate Lise Worthen-Chaudhari awarded 2016 Early Career Innovator of the Year

As Ohio State continues to expand its role in the commercialization of research, it is important to create an environment that facilitates and rewards research creativity and entrepreneurship. To support and stimulate entrepreneurial activity among Ohio State researchers, three university-wide awards were presented on January 25, 2017, to Ohio State’s most successful entrepreneurs.

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Chronic Brain Injury

Ohio State Receives $1.7M for Spinal Cord Injury Research

Scientists from The Ohio State University College of Medicine are recipients of a five-year, $1.7 million award from the National Institute of Neurological Disorders and Stroke for spinal cord injury research.

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