Chronic Brain Injury

CBI is accepting seed grant applications through November 1, 2019.
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ADVANCING THE PREVENTION, DETECTION, AND TREATMENT OF BRAIN INJURIES

Our brain is the body's most complex organ. It makes us who we are. It is critical to our abilities to speak, think, remember, interact and move. Even mild brain injuries can have persistent, chronic effects that affect future health and wellbeing. However, the detection of the extent, phase and severity of brain injury continues to be elusive.

To accelerate discovery, more than 250 experts in the fields of engineering, psychology, neuroscience, speech and hearing science, rehabilitation and medicine are forming and scaling teams to translate knowledge, and expand capacity to implement practical solutions through public-private partnerships. We are:

  • Developing methods for detecting the presence and extent of brain injuries and chronic neurodegenerative diseases with real-time monitoring of “rare” biological moieties
  • Deepening an understanding of why even mild brain injuries (e.g., concussions) have persistent, chronic effects that can provoke early-onset dementia, and developing personalized interventions in the case of injury.
  • Understanding the effects on cognitive abilities, psychological wellbeing and social competence from trauma on the brain's structures and functions, and conditions like Alzheimer Disease.
  • Creating new and improved approaches and techniques for imaging the brain with emerging sensor technologies and data analysis methods, and breakthroughs in neural interfacing technology, neural prosthetics and biotronic engineering technologies.
  • Studying the role of immune cells and responses after traumatic brain injury to develop intervention strategies to decrease brain damage and translate NIH-funded clinical trials for acute neurological conditions into best practice assessment techniques.

Ohio State is advancing how we understand and approach brain injury — from molecular investigations in the laboratory to clinical applications at patients' bedsides.

Program Team

Faculty Director

Jonathan Godbout, PhD

Program Manager

Kedar Hiremath, MBA, MPH

Program Coordinator

Julie Hannahs

News

Chronic Brain Injury

Ohio State receives inaugural NIH/NEA Sound Health Initiative award

CBI faculty Yune Lee (Speech & Hearing Sciences) received an NIH R21 award to study the neural mechanisms underlying language recovery through rhythm therapy for people with aphasia. Aphasia is a language disorder common in moderate and severe brain injury that limits a person's ability to speak - but many people with aphasia can sing. Dr. Lee and his collaborators are testing if rhythm-based therapy delivered through a video game, TheraBeat, will create subsequent changes in brain function using fMRI and fNIRS imaging. This is one of 15 inaugural awards through the Sound Health Initiative, which features a partnership between NIH and the National Endowment for the Arts.

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Chronic Brain Injury

Brain injury common in domestic violence

New research by CBI affiliate Juliana Nemeth suggests that brain injury caused by blows to the head and by oxygen deprivation are likely ongoing health issues for many domestic violence survivors. Because of poor recognition of these lasting harms, some interactions between advocates and women suffering from the effects of these unidentified injuries were likely misguided.

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Chronic Brain Injury

CBI 2019 Summer Undergraduate Research Fellows

CBI launched its Summer Undergraduate Research Fellowships (SURF) Awards in Spring 2019 to support training and development of outstanding Ohio State undergraduates through participation in basic, clinical, and translational research. SURF Fellows complete a research project with CBI faculty mentors during the summer semester. Congratulations to the inaugural SURF Fellows who will each receive $4,000 stipends for their project. Sebastian Bejarano, College of Engineering (Mentor: Liang Guo, PhD) Mahin Hossain, College of Medicine (Mentor: Jan Schwab, MD, PhD) Praneethkumar Madhu, College of Medicine (Mentor: Harry Fu, PhD) Matthew Moritz, College of Arts & Science (Mentor: Yune Lee, PhD)

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Chronic Brain Injury

Insights: Scalpel-free Surgery for Brain Health

Vibhor Krishna, MD is featured by Ohio State Insights for his work on developing focused ultrasound technology that can remove diseased or cancerous brain tissue, restore fine movement, and help deliver medications to the brain. People living with complications from brain injury such as movement disorders and Alzheimer's may benefit from these techniques in the future.

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Chronic Brain Injury

CBI 2019 Brain Health Hack Winners

CBI's annual weekend workshop for undergraduates saw teams build and develop mobile and virtual reality applications that address brain health research and clinical needs. Teams often bridged engineering and health sciences disciplines, and completed their applications in under 20 hours. Several projects were suggested by Ohio State and Nationwide Children's Hospital faculty, and successful teams will continue to develop their work in partnership with the sponsors. Congratulations to winning teams 119, Project Velvet, and VrNS!

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Chronic Brain Injury

CBI 2018 Paper of the Year

Congratulations to Harry Fu, PhD, for winning the CBI 2018 Paper of the Year! Harry is an Assistant Professor in the Department of Neuroscience, and was awarded $500 and a plaque for his accomplishment. This award recognizes scientific impact and contribution to chronic brain injury research.

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Chronic Brain Injury

Subtle hearing loss while young changes brain function

Cranking up your headphones or scrambling for a front-row spot at rock shows could be damaging more than your hearing. "Hearing loss, even minor deficits, can take a toll in young people - they're using cognitive resources that could be preserved until much later in life," says Yune Lee, a CBI affiliate and assistant professor in Speech & Hearing Sciences. "Most concerning, this early hearing loss could pave the way for dementia."

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Chronic Brain Injury

Jonathan Godbout named interim faculty director for Chronic Brain Injury

Jonathan Godbout, PhD, has been named interim faculty lead of the Chronic Brain Injury (CBI) program, a focus area of the $500 million Discovery Themes initiative created by Ohio State to address global challenges.

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Chronic Brain Injury

New Thoughts About Brain Disorders: Electrical Engineering Research Delves into Mind

People with brain disorders such as Alzheimer’s and Parkinson’s disease could probably tell you about the limitations of current treatments. But what if they could have better options in the future — options beyond currently approved medications or devices?

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Chronic Brain Injury

CBI affiliate Lise Worthen-Chaudhari awarded 2016 Early Career Innovator of the Year

As Ohio State continues to expand its role in the commercialization of research, it is important to create an environment that facilitates and rewards research creativity and entrepreneurship. To support and stimulate entrepreneurial activity among Ohio State researchers, three university-wide awards were presented on January 25, 2017, to Ohio State’s most successful entrepreneurs.

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Chronic Brain Injury

Seed grants available for traumatic brain injury research

Chronic Brain Injury, a Discovery Themes program, is offering up to five seed grants of $25,000 for interdisciplinary research projects on traumatic brain injury, concussion and related chronic effects such as cognitive impairment. Submit letters of intent by the deadline of Monday (10/15).

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