DISCOVERY THEMES

CHRONIC BRAIN INJURY PROGRAM

ADVANCING THE PREVENTION, DETECTION, AND TREATMENT OF BRAIN INJURIES

The brain is the body's most complex organ. It makes us who we are. It is critical to our abilities to speak, think, remember, interact, and move.

The Ohio State University is advancing how we understand and approach brain injury as a chronic condition. Even mild brain injuries can have persistent, long-term effects that impact our future health and wellness. Understanding, detecting, treating, and preventing these effects is essential to solving the silent epidemic of traumatic – or rather, chronic – brain injury.

ABOUT US

To accelerate discovery, our scientists and clincians are forming interdisciplinary teams that are translating knowledge, partnering with industry and community organizations, and expanding capacity to implement practical solutions.

Our researchers are:

  • Deepening an understanding of how brain injuries result in visible and chronic conditions and higher risk for dementia and movement disorders
  • Studying the mechanisms of the immune system's response to neurotraumas that will inform pharamlogical, rehabilitative, and arts-based interventions
  • Developing new approaches to imaging, sensing, and clinical data analytics that better detect, monitor, and predict the trajectories of brain injuries

We are investing in people, projects, and resources that enable convergence research in the lab, the clinic, and the community. Learn more about our program and offerings at the links below.

We've built a network of over 100 research labs at Ohio State in fields spanning neuroscience, electrical engineering, psychology, public health, music, and rehabilitation sciences. Through our community partners, we are building a coalition of professionals and patients to help brain injury survivors recover and thrive.

CBI Faculty Spotlight

John Corrigan, PhD

John.Corrigan@osumc.edu

Emeritus Professor, Department of Physical Medicine and Rehabilitation

Director, Ohio Valley Center for Brain Injury Prevention and Rehabiliation


Dr. Corrigan serves as project director for the Ohio Regional TBI Model System, a multi-center, longitudinal research program funded by the National Institute on Disability and Rehabilitation Research. Dr. Corrigan has been the PI and co-PI of the Ohio Regional Traumatic Brain Injury Model System since 1997 and chaired the Executive Committee of the TBI Model Systems Project Directors from 2007-2017. He is the Director of the Ohio Brain Injury Program, which is the designated lead agency in the state of Ohio for policy and planning related to living with brain injury. Dr. Corrigan is also a member of the Board of Directors of the Brain Injury Association of America and Editor-in-Chief of the Journal of Head Trauma Rehabilitation. He has received local and national awards for his service and research in the field of brain injury rehabilitation.

Learn more about Dr. John Corrigan

NEWS

Chronic Brain Injury

Congratulations to the 2020 CBI SURF Fellows!

We at CBI are proud to award three Summer Undergraduate Research Fellowships (SURF Awards) to Ohio State undergraduate students pursuing brain injury research with our faculty affiliates. Each student will spend the summer completing a research project and will present these projects at an upcoming seminar or conference. Fellowships support the student’s time, while the mentor provides project funding and training... Join us in congratulating our new fellows!

Read More

Chronic Brain Injury

Dr. Quatman-Yates Publishes the First APTA CPG for the Care-Management of Concussion

Dr. Quatman-Yates and her team have made great progress in this front with their recently published Clinical Practice Guidelines (CPG) for the physical therapy management of concussion, which have been endorsed by the American Physical Therapy Association and its affiliated academies. This is the first CPG to provide detailed guidance on care-management strategies for physical therapists that are treating patients who have experienced a potential concussive event. Prior CPGs for concussion management have largely focused on sideline management, acute treatment, and return to sport protocols.....

Read More

Chronic Brain Injury

2019 CBI Paper of the Year

Andrea Tedeschi, PhD., Assistant Professor of Neuroscience, won the 2019 CBI Paper of the Year for his work, "ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS", which was published in Neuron. This work described essential mechanisms for axonal regeneration in neurons following central nervous system injury, which may inform future regenerative interventions. Several publications were nominated for this annual award, and are listed on our Projects & Highlights page. Read Dr. Tedeschi's paper at the link below.

Read More

Chronic Brain Injury

CBI 2019 Brain Health Hack Winners

CBI's annual weekend workshop for undergraduates saw teams build and develop mobile and virtual reality applications that address brain health research and clinical needs. Teams often bridged engineering and health sciences disciplines, and completed their applications in under 20 hours. Several projects were suggested by Ohio State and Nationwide Children's Hospital faculty, and successful teams will continue to develop their work in partnership with the sponsors. Congratulations to winning teams 119, Project Velvet, and VrNS!

Read More

Chronic Brain Injury

CBI 2019 Summer Undergraduate Research Fellows

CBI launched its Summer Undergraduate Research Fellowships (SURF) Awards in Spring 2019 to support training and development of outstanding Ohio State undergraduates through participation in basic, clinical, and translational research. SURF Fellows complete a research project with CBI faculty mentors during the summer semester. Congratulations to the inaugural SURF Fellows who will each receive $4,000 stipends for their project. Sebastian Bejarano, College of Engineering (Mentor: Liang Guo, PhD) Mahin Hossain, College of Medicine (Mentor: Jan Schwab, MD, PhD) Praneethkumar Madhu, College of Medicine (Mentor: Harry Fu, PhD) Matthew Moritz, College of Arts & Science (Mentor: Yune Lee, PhD)

Read More

Chronic Brain Injury

Jonathan Godbout named interim faculty director for Chronic Brain Injury

Jonathan Godbout, PhD, has been named interim faculty lead of the Chronic Brain Injury (CBI) program, a focus area of the $500 million Discovery Themes initiative created by Ohio State to address global challenges.

Read More

Chronic Brain Injury

CBI 2018 Paper of the Year

Congratulations to Harry Fu, PhD, for winning the CBI 2018 Paper of the Year! Harry is an Assistant Professor in the Department of Neuroscience, and was awarded $500 and a plaque for his accomplishment. This award recognizes scientific impact and contribution to chronic brain injury research.

Read More

Chronic Brain Injury

CBI affiliate Lise Worthen-Chaudhari awarded 2016 Early Career Innovator of the Year

As Ohio State continues to expand its role in the commercialization of research, it is important to create an environment that facilitates and rewards research creativity and entrepreneurship. To support and stimulate entrepreneurial activity among Ohio State researchers, three university-wide awards were presented on January 25, 2017, to Ohio State’s most successful entrepreneurs.

Read More

Chronic Brain Injury

Brain injury common in domestic violence

New research by CBI affiliate Julianna Nemeth suggests that brain injury caused by blows to the head and by oxygen deprivation are likely ongoing health issues for many domestic violence survivors. Because of poor recognition of these lasting harms, some interactions between advocates and women suffering from the effects of these unidentified injuries were likely misguided.

Read More